FDA advisory committee votes against Pfizer booster shot per Bloomberg

[TheRealNorth]

15. The vaccine could probably still be given "off label"

But in those cases, insurance would probably not pay for it.

Also, I suspect boosters will eventually happen. The issue was the data on waning immunity presented by Pfizer was not independently reviewed by experts.

There were other questions about what Pfizer was measuring (they measured only antibodies), while they failed to look at other parts of the immune system. The point is that as you get farther and farther away from the exposure to an antigen (the virus or the vaccine), most of your antibodies (IgG antibodies) against Covid will go away. However, the immune system maintains other types of antibodies at low levels that will help ramp up production of IgG if an infection is encountered again.

Now there may be questions about whether you are more likely to be an asymptomatic carrier, or experience mild symptoms, if the amount of IgG gets too low (as it takes the body time to make more). This is why boosters are more important for immune-compromised individuals, who may have a tougher time making more antibodies quickly.

There is also the potential issue of new strains of Covid with resistance to the current vaccine, but that would probably mean we would need new versions of the vaccine, kind of like the new versions we need for the flu vaccine.