UCSF study suggests novel treatment for fending off chronic age-related diseases: Moisturizer EDITED

[elleng]

Last edited Sat Mar 16, 2019, 03:26 PM - Edit history (1)

'A new UCSF pilot study has a simple suggestion for a treatment to fend off serious age-related issues like Alzheimer's, diabetes and heart disease. The best part? You might already own it.

University researchers in tandem with the San Francisco Veterans Administration (VA) Health Care System now have reason to believe that inflammation of the skin may further the development of multiple chronic diseases, and one way to help fix the issue is by applying reparative moisturizer.

The study's authors write that as skin begins to lose moisture and deteriorate around age 50, it begins to experience a breakdown of the "permeability barrier." The barrier is meant to both keep water in the body and act as a shield from sinister pathogens outside our bodies.'>>>

https://www.sfgate.com/science/article/UCSF-study-skin-moisturizer-inflamation-disease-13691930.php?

EDIT: A friend's friend wrote: I was curious about this as well, as the summary didn't identify the moisturizer (assuming that it was a name brand), or specifics of the optimal mix of "cholesterol, free fatty acids, and ceramides." So I "used the Google" and asked for "moisturizers with ceramides." The first result was a link to a list of "The 8 Best Ceramide Moisturizers to Buy in 2019," and first on the list was CeraVe, which was described as containing "the specific ceramides that are necessary for replacing and retaining your skin’s moisture. It also has the cholesterol and fatty acids needed to help those ceramides sink into your skin, as well as hyaluronic acid for even better absorption."

[htuttle]

1. Well, that's auspicious timing

About two weeks ago, I started using a clinical moisturizer every day, since my skin was turning into itchy treebark with the abuse it's taken this extreme Wisconsin winter (and sitting right next to a heater vent every night).

Fending off Alzheimer's, diabetes and heart disease would be a plus.

[elleng]

2. Sounds like a good idea!

[Laffy Kat]

3. Won't hurt anything!

Pass the Vaseline.

[still_one]

4. If you read the article, it is a special type of moisturizer noted for its ratio of three lipids

known to be beneficial to skin health.

[Laffy Kat]

5. I went back and re-read.

Great. Someone will eventually bottle it and make millions. Yes, I'm kind of cynical.

[still_one]

7. Probably. They need more data, and double blind study. They are making some pretty extraordinary

claims

[nilram]

9. The company producing it is in a press release from UCSF

https://www.ucsf.edu/news/2019/03/413576/skin-repair-eliminates-inflamm-aging-linked-chronic-disease

"Conflicts: Elias and Man serve as consultants to South Korea–based Neopharm, Ltd., which produces the lipid-balanced moisturizer used in the study. An invention disclosure has been filed with the UCSF Office of Innovation, Technology & Alliances for the concept of preventing/treating systemic disorders using strategies that improve epidermal function."

Ooh, and I found the pre-release version of the article,

https://onlinelibrary.wiley.com/doi/abs/10.1111/jdv.15540

The product isn't named there, either. Just "an emollient, previously shown to improve epidermal function".

[still_one]

11. Interesting, and they correctly noted possible conflicts. Thanks

[diane in sf]

6. Vaseline is petroleum, don't use it on your skin. Coconut oil would be a lot healthier and you can

buy vats of the organic version cheaply at Costco. Stuff with mineral oil, also petroleum, pulls fat soluble vitamins out of your skin.

[Laffy Kat]

8. I had no idea. Thx.

[mopinko]

10. or crisco.

used to be a dermatologist that was a frequent guest on the local npr station who swore that crisco was the perfect moisturizer.

[PoindexterOglethorpe]

12. I've been moisturizing my face since, I can't remember when.

Probably my 30s. I'm 70 now.

I also put lotion on my entire body after my daily shower, and have been doing that for nearly 30 years.

I've always had dry skin.

[lillypaddle]

13. Just ordered

CeraVe from Amazon. Thanks for posting

[elleng]

14. You're welcome.

I think I've seen it at my grocery story, in the Lubriderm 'aisle!' Will pick it up when I've run out of Lubriderm.