The maximum number of US Senate seats the Democrats will gain in 2022 is 3.

[nkpolitics1212]

Democrats will win all of the Democratic held US Senate seats up for re-election in 2022.
37)HI(Schatz-D)
38)NY(Schumer-D)
39)VT(Welch-D)
40)CA(Padilla-D)
41)MD(Van Hollen-D)
42)CT(Blumenthal-D)
43)WA(Murray-D)
44)OR(Wyden-D)
45)IL(Duckworth-D)
46)CO(Bennet-D)Likely D
47)NH(Hassan-D)Likely D
48)AZ(Kelly-D)Lean D
49)NV(Cortez Masto-D)
50)GA(Warnock-D)
Democrats will win 3 Republican held US Senate seats up for re-election in 2022
51)PA(Fetterman-D)
52)WI(Barnes-D)
53)NC(Beasley-D)

Republicans will win OH(Mandel-R) and FL(Rubio-R) by a narrow to high single digit margin.

[PortTack]

1. Don't know about OH..Tim Ryan is really well liked and has a strong base in several areas.

[nkpolitics1212]

2. The problem with OH is OH is a red state. Biden lost OH by a 8 percent margin.

Sherrod Brown is the only current Democratic statewide elected official in OH.

The 2022 OH US Senate Election is similar to the 2006 TN US Senate Election.
The Democratic nominee in the 2006 TN US Senate Election- Harold Ford Jr. narrowly lost.

[ColinC]

3. For me, if Brown can win Ohio as well as he has as a pretty liberal senator

So can Tim Ryan who I think is arguably not quite as liberal as Brown.