The number of US Senate seats the Democrats will have after 2022 is between 49 to 51 seats.

[nkpolitics1212]

Safe D
37)VT(Leahy-D)
38)HI(Schatz-D)
39)NY(Schumer-D)
40)CA(Padilla-D)
41)MD(Van Hollen-D)
42)CT(Blumenthal-D)
43)OR(Wyden-D)
44)WA(Murray-D)
45)IL(Duckworth-D)
Likely D
46)CO(Bennet-D)
Lean D
47)NH(Hassan-D)
48)NV(Cortez Masto-D)
Tilt D
49)AZ(Kelly-D)
Tossup
50)PA(Fetterman-D)
51)GA(Warnock-D) will be decided in the 12/2022 or 1/2023 General Election runoff.
Tilt R
52)WI(Johnson-R vs Barnes-D) will be similar to 2010(Johnson-R vs Feingold-D) and 2016(Johnson-R vs Feingold-D)
Lean R
53)NC(Budd-R vs Beasley-D)
54)OH(Mandel-R vs Ryan-D)
Likely R
55)FL(Rubio-R vs Demings-D)