The maximum number of US Senate seats up for re-election in 2022 that the Democrats will win is 21.

[nkpolitics1212]

1)HI(Schatz-D) 37
2)NY(Schumer-D) 38
3)CA(Padilla-D) 39
4)MD(Van Hollen-D) 40
5)CT(Blumenthal-D) 41
6)VT(Leahy-D) 42
7)OR(Wyden-D) 43
8)WA(Murray-D) 44
9)IL(Duckworth-D) 45
10)CO(Bennet-D) 46
11)NV(Cortez Masto-D) 47
12)NH(Hassan-D) 48
13)AZ(Kelly-D) 49
14)GA(Warnock-D) 50
15)PA(Fetterman-D) 51
16)WI(Godlewski-D) 52
17)NC(Beasley-D) 53
18)FL(Demings-D) 54
19)OH(Ryan-D) 55
20)IA(Finkenaur-D) 56
21)AK(Gross-D/I) 57.

The 3 US Senate seats the Democrats have to win to get 60 seats.
22)KY(Booker-D)58
23)MO(Lucas-D)59
24)IN(McDermott-D)60