The minimum number of US Senate seats that the Democrats will win in 2022 is 14.

[nkpolitics1212]

Democrats will win 12 out of 14 Democratic held US Senate seats up for re-election
1)HI(Schatz-D)
2)NY(Schumer-D)
3)VT(Leahy-D)
4)MD(Van Hollen-D)
5)CA(Padilla-D)
6)WA(Murray-D)
7)CT(Blumenthal-D)
8)IL(Duckworth-D)
9)OR(Wyden-D)
10)CO(Bennet-D)
11)AZ(Kelly-D)
12)NV(Cortez Masto-D)

Democrats could lose NH- if Sununu-R is the Republican nominee and GA in the January 2023 runoff.
Democrats will win 2 Republican held US Senate seats up for re-election in 2022.
1)PA(OPEN Toomey-R)Fetterman-D
2)WI(Johnson-R or OPEN) Barnes-D, Godlewski-D, Kaul-D, and Kind-D could defeat Johnson-R.